How to Pick The Best Enzyme Cleaner For Cat Urine in 2023

Cat in words comforting, sweet, and furry little companion. You feel special when little cute furry thing is roaming around and following you around the house, sleeping, and cuddling with you. But if you make a list of the worst domestic smells and stains, then number one is the cat urine. Yes, we all have a litter box for the cat, but for some reason like- medical, mental or physical, cats may urinate in the house. As the cat urine contains different substances with bacteria, for this, the urine comes with a strong odor.

And it is essential to use the enzyme cleaner because the urine smell makes the cat urine in the same place again and again. After reviewing dozens of cleaners, you will get the top ten best natural enzyme cleaners for cat urine available in the market.

Cat urine comes with a stinky and robust odor. It is because cat urine is concentrated as the cat evolves less water. Now the question is, do the odor go away? The answer is yes, but you have to use the perfect enzyme cleaner to clean the urine.

What is an enzyme cleaner?


Enzymes are biological composites that help to boost up the chemical reactions. In the environment, you will find hundreds and thousands of enzymes that speed up the process of different household waste. The cleaners with the enzymes get powerful and clean the cat urine odor like a pro. It is because the enzyme breaks the biological substances like oils, proteins, fats, and starches and turns them into hydrogen, oxygen, and carbon. So the enzyme cleaner makes your environment safe and clean.

How to Pick an Ideal Enzyme Cleaner for Your Cat?

As there are lots of enzyme cleaners to pick with lots of consideration, you have to know the main points to pick the right one for your house. Let’s have a look at the consideration points:

Safety is a priority. You must ensure the safe use of the chemical in your house. Follow the instruction of the chemical used to make sure that they are suitable for house use or commercial use.

Your cleaner has to contain the right enzymes in the right amount. When you are looking for the urine cleaner, just look for these three enzymes:

Protease: Blood and urine that are protein-based can be removed with this enzyme.

Amylase: This enzyme breaks down the sauces, starches, and eggs. So, it is easy to remove the urine stain with this enzyme.

Lipase: Any kinds of fat and oily stains can be getting rid of easily with this enzyme.

Pick the packaging type that will be helpful for you. There are two types of packaging types, one is a spray bottle, and the other one pours bottle.

The stain of cat urine is not easy to remove like any other stains. Some enzyme cleaners don’t work properly like they tend to mask the odor instead of getting rid of the smell. You have to pick the enzyme cleaner that gives you a 100% guarantee to provide you with an odor-free environment.

The enzymes come with three levels of concentration – domestic, commercial, and industrial. For high concentration, your fabric may get bleach, and weak concentration requires frequent use of the cleaner.

Pick the cleaner that is scented. You will not need extra air freshener.

Know your surface type before picking the urine cleaner. Because some cleaner works on different surfaces, choose the one that is well-suited with many surfaces.

The Top 10 Enzyme Cleaner for Cat Urine Reviews in 2023

Best Enzyme Cleaner For Cat Urine
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  1. Rocco & Roxie Professional Strength Stain & Odor Eliminator:

Even your cat is well-behaved in the world, an accident happens. You will have to deal with the cat urine once in your lifetime. Don’t panic! You have the best enzyme cleaner Rocco & Roxie Stain & Odor Eliminator to use. This odor eliminator has the bio-enzymatic formula that is strong and works professionally by releasing the bacteria. These active bacteria work on remaining ammonia and eliminate the stain and the odor for good.

Rocco & Roxie Professional Strength Stain & Odor Eliminator
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Rocco & Roxie Professional Strength Stain & Odor Eliminator is not only good for removing odor and stains, but it is highly recommended for the safe and gentle formula for kids’ and pets’ environment.
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The best thing about this stain eliminator that it is color-safe and chlorine-free. So, you can tell it is safe and gentle to use in any environment. You can use this stain remover on every surface any time you want. It is safe to use on any carriers, boxes, carpets, furniture, and anywhere. You can use it in the laundry also. Just spray and soak the stain for 10 minutes then wash it in the machine. It will come out good as new.

Pros Cons
  • Completely removes the unbearable smell of cat urine from the carpet
  • Works smoothly on any surface.
  • Chlorine-free and color-safe.
  • Easy to apply for the spray bottle.
  • The odor is durable and lasts long.


  1. TweetMint All-Purpose Non-Toxic Enzyme Cleaner:

TweetMint Enzyme Cleaner is the best cleaning product that comes with a safe, strong, but non-toxic formula. You can clean your pet’s stain and urine odor easily with this product. The cleaner is concentrated so you can use it for a long time.

The best thing about this enzyme cleaner is entirely natural and versatile cleaner. You can use this cleaner on any surface and furniture like sofa, bed, chair, etc. just you have to follow the usage instruction properly.

TweetMint All-Purpose Non-Toxic Enzyme Cleaner
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TweetMint All-Purpose Non-Toxic Enzyme Cleaner comes with natural ingredients and for multipurpose use. You can tell you are using high-quality products at a reasonable price.
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As it is known as a natural product, let’s know about the ingredients – you will find sodium borate, peppermint oil, enzymes, glycerin, surfactant blend anionic, or nonionic, purified water. The best thing about these ingredients is they are pH balanced and hypoallergenic, biodegradable, and nontoxic.

The cleaner comes highly concentrated. So, you can use it in a little amount, and the 32oz bottle will last long.

It is a super safe cleaner. You can clean the urine spot without wearing your globe as it is easy on the skin. And the smell is soothing. You will not feel any irritation or breath problems while working with this cleaner.

You can use it on mites, scabies easily. It is really a safe and life-saving cleaner.

Pros Cons
  • Cleans everything with ease.
  • Smells great
  • Natural ingredients.
  • Safe to use
  • The USA made cleaner.
  • Not for clothes parasite


  1. TriNova Natural Pet Stain and Odor Remover Eliminator:

When your pet makes a mess in one area accidentally just once and if you don’t clean the area properly, then your pet will do the same thing in the same spot every day. So, to clean the spot completely without any mark, you have to use TriNova Natural Pet Stain and Odor Remover Eliminator.

This cleaner is a natural cleaner, and it is 100%. The packaging of this cleaner uses the green standard as the ingredients are organic and natural.

TriNova Natural Pet Stain and Odor Remover Eliminator
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TriNova Natural Pet Stain and Odor Remover Eliminator are highly recommended for not only good for eliminating stain and odor but also for herbal fragrance.
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In the formula, you will find a mixture of natural enzymes that are strong to work on the root of the odors and stains. The enzymes at first break the odor and stains secondly dry them, and lastly, eliminates them. When you finish your work, you will find your carpet useful as new without any bad smell.

This enzyme cleaner is safe around pets and kids. It is obvious that your pet will find a comforting place to do the “thing.” Your kid and you also like space. So this cleaner works in the safe zone to make the place clean for your kid and you. As the ingredients are natural and non-toxic, you will not have to worry about chemical reactions.

You use this cleaner anywhere you want, be it mattress or laundry or clothes. You can use it on little animals like mice, hamsters, etc.

Pros Cons
  • It comes with natural ingredients.
  • Have herbal fragrance to eliminate the urine odor
  • Not too intense
  • Don’t work on dried stains.


  1. BUBBAS Super Strength Commercial Enzyme Cleaner:

BUBBAS Super Strength Commercial Enzyme Cleaner is an instant stain remover. It has the strongest and powerful formula to use. The formula is scientifically potent to clean the carpets, rugs, flooring, and make them safe for your kids and pet. Yet the odor and stains are eliminated permanently.

BUBBAS Super Strength Commercial Enzyme Cleaner
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BUBBAS Super Strength Commercial Enzyme Cleaner stays strong till every reuse as some cleaner gets weak after every use.
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There is a natural inactive bacterium in the formula that becomes active when it comes in contact with the pet urine. The enzymes attack the stain by getting in billions in number and destroys it completely. After completing the destroying part, the bacteria turn inactive again.

This stain cleaner can be used in any area and furniture you want. You can also use this cleaner to remove the shoe odor, removing carpet stains, eliminating the odor that comes from the sofa. You can use it in your vehicle cleaning also.

This cleaner works like expensive ones. I can say the smell is much better than any other brand. The smell of this enzyme cleaner is like refreshing fabric spray.

Pros Cons
  • Instant stain and odor removal
  • Smells great
  • Excellent cleaner
  • Little weak on tough stains.


  1. Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator:

Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator comes with six plant-based enzymes. So, you can tell this stain removing product is super powerful.

Enzymes are always considered as a safe but effective ingredient to remove and destroy the cat urine stains and odors. This cleaner comes with six plant-based bio-enzymes that are ready to tackle all kinds of stains and remains. It is completely safe and easy on any surface or fabric.

Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator
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Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator is 99.5% natural and has a concentrated solution. With the formula, the stain gets removed, the odor goes away, and your fabric stays fresh and clean.
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This cleaner comes with calcium chloride, coconut fatty acid, Benzisothiazolinone,  Mannanase, Cellulase, Pectinase, Sodium Citrate, Lipase, Sodium Borate, Amylase, Protease, Vegetable Glycerin, Propanediol, Decyl Glucoside, C10-C16 Alcohol Ethoxylate, Purified Water. All are natural, non-bleaching, non-toxic, gluten-free, vegan, and hypoallergenic.

With this stain cleaner, you can wipe away any stains that come from mud, watermelon, red wine, grass, blood, berries, sweat, tomato sauce, oil, cosmetics, etc. Be the stains are on cloth, bedding, car seats, linens, floor mats, carpets, they can be removed easily.

The cleaner is safe for your kids and pets. As it has plant-based ingredients, so you can use it on any cloth and fabrics.

Pros Cons
  • Natural stain remover.
  • It works like magic.
  • Best for any surface and fabrics.
  • Discolors some cloth fabrics.


  1. Amazing Solutions Pet Odor Eliminator and Stain Remover:

Having a pet in the house is like having a trustful companion for a lifetime. But the only thing to bear is the urine accidents. The worst thing is if you cant clean the area properly, your pet will start an unhygienic cycle of doing a pee in the same area and destroying your carpet and surface. To break this unwanted cycle, you have to use Amazing Solutions Pet Odor Eliminator and Stain Remover. With this odor remover, the stain and the odor will go away for good. This cleaner has powerful but safe cleaning enzymes that promise a safe environment for all.

Amazing Solutions Pet Odor Eliminator and Stain Remover
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Amazing Solutions Pet Odor Eliminator and Stain Remover is best for carpet and hardwood floors at a reasonable price.
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A maximum urine smell eliminator has an overpowering smell that fails to remove the urine smell after use. Amazing Solutions Pet Odor Eliminator works effectively with a pleasant smell that can remove the odor properly without damaging anything. You will get a deep clean carpet with the beautiful smell in the house for this enzyme cleaner.

It is a common problem to have that odor in the pet house. Thanks to this cleaner, the home will stay refreshing and clean.

For the natural enzyme in the formula of the cleaner, the urine stain and odor eliminate with ease. You will not have to scrub your carpet. Just follow the instruction, and your stain and odor both will go away.

Pros Cons
  • Amazing stain and odor remover.
  • Cleans perfectly.
  • The smell is refreshing.
  • Not for stubborn stains.


  1. Mister Max Unscented Anti Icky Poo Odor Remover:

If you are looking for a complete environment-friendly pet urine odor cleaner, then Mister Max Unscented Anti Icky Poo Odor Remover is just perfect to use. This enzyme cleaner promises a safe environment. It is safe for kids and pets.

Maximum odor remover tries to hide the odors, but anti icky poo eliminates the urine odor. It works on any type of vomit and urine of rodents, humans, skunk, dog, and cat. You will not have a trace of the pee odor after using this odor remover.

Mister Max Unscented Anti Icky Poo Odor Remover
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Mister Max Unscented Anti Icky Poo Odor Remover is for them who are searching for a green and environment-friendly enzyme cleaner.
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In the formula of this cleaner, there are live bacteria that work to eliminate the organic bacteria. There are microbes in the formula which are friendly. These microbes destroy the odor by eating the source.

The enzyme cleaner is non-toxic. If you have used other odor eliminators in your house, then you have to use P-BATH before using this enzyme cleaner.

Pros Cons
  • Best enzyme cleaner for carpet.
  • Safe cleaner.
  • Smell is refreshing
  • The surface gets a little sticky after use.
  1. Simple Solution Extreme Pet Stain and Odor Remover:

Those who are busy but love pets must keep this stain and odor remover at home. This cat urine stain remover promises to give a healthy and clean environment by any cost.

The cleaner has mild detergent, Purified water, fragrance, non-pathogenic bacteria, natural enzymes, and denatured ethanol. All ingredients are natural and non-toxic.

Simple Solution Extreme Pet Stain and Odor Remover
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Simple Solution Extreme Pet Stain and Odor Remover have a new multi-functional sprayer that helps the odor stain remover work quickly and safely.
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Simple Solution Extreme Pet Stain and Odor Remover clean tough stains like vomit, feces, and urine with confidence. It is three times stronger than any normal stain and odor remover. The best thing about this stain remover is the cleaner discourages odors coming back. This cat urine stain and odor remover are designed to remove the tough odors and stains.

The stain and odor remover has a professional enzyme formula and pro-bacteria that works by breaking down and eliminate the odors and stains easily but professionally.

This stain and odor remover comes in patented 3 in 1 sprayer. As the mist is best for surface stains, the foam is for embedded stains, and the stream is best to control the odor.

Perfect to use on any kind of furniture, carpet, cloth, bedding. You can use it safely as it is safe for any environment.

Pros Cons
  • Amazing odor and stain cleaner.
  • Effective cleaner.
  • The smell is excellent.
  • Easy to use.
  • It takes time to eliminate old stains.


  1. Life Miracle Enzyme Cleaner & Pet Odor Eliminator Concentrate:

Life Miracle Enzyme Cleaner & Pet Odor Eliminator Concentrate is that kind of enzyme cleaner that works effectively but comes in non-toxic and natural ingredients.

With this cleaner, you can eliminate the odor and stain from their source. As the cleaner has a natural enzyme, so it works differently than chemical ingredients. Chemical cleaners make the surface slippery. Moreover, the toxic chemical ends up in the human organs like eyes, lungs, blood, skin after frequent use. But this natural cleaner promise safe to use and means no harm to any human organs.

Life Miracle Enzyme Cleaner & Pet Odor Eliminator Concentrate
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Life Miracle Enzyme Cleaner & Pet Odor Eliminator Concentrate is an economical product with versatile and safe use.
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This pet odor eliminator comes with an all-purpose enzyme cleaner. You can use this cleaner on any surface, fabric, furniture quickly. You can also use it in laundry to remove gross stains from your cloth.

We have a wrong concept that only chemical is required to clean tough stains, especially pet urine stains. But this cleaner has those powerful but safe enzymes that eliminate the stains by breaking and eliminating the odor and stains. The cleaner doesn’t mask the odor; they remove it instantly. You will not have to worry about any toxic remaining after cleaning with this cleaner.

This cleaner is eco-friendly, allergy-free, non-toxic, delicate greywater, and safe for colors.

Pros Cons
  • Best stain and odor treatment.
  • Safe for humans and pets.
  • Refreshing smell.
  • It requires time to clean the stain permanently.


  1. Spartan Consume Nature’s Way Cleaner Odor Eliminator:

Lastly, let’s talk about an excellent pet urine odor eliminator that works powerfully on any stains like vomit, food, blood, feces, urine. The stains get removed permanently without leaving any chemical residue.

Spartan Consume Nature's Way Cleaner Odor Eliminator
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Best cat urine stain remover at a reasonable price. Those who are looking cheap but effective cat urine stain remover then Spartan Consume Nature’s Way Cleaner Odor Eliminator is recommended.
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You can pour this odor eliminator in any sour drains to unclog. You can use this cleaner on your carpet to remove every kind of stains in any area.

The best thing about this product is the cleaner doesn’t try to hide the odor; it eliminates the odor.

Pros Cons
  • Powerful enzyme cleaner.
  • Safe to use.
  • It can be used on any surface.
  • It can be used on wood floors but not all the time.



If you have a pet in the house, the first duty is to train him and make him well behaved, especially about the potty one. If your pet has a urination problem, at first fix the problem. Then look for the best enzyme cleaner to deal with the stain and odor. I hope this review will help to get the best product from the product to keep your home clean and refreshing.

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